A serious disease that can be seriously misunderstood
LGSOC is distinct and different from the more common high-grade serous ovarian cancer (HGSOC) and should be treated differently by your medical team. Get the facts about LGSOC.
Low-grade serous ovarian cancer symptoms are similar to other cancers and different diseases, like irritable bowel syndrome (IBS)—LGSOC may be overlooked and take a long time to diagnose.
Treatment options
Clinical trials
Clinical trials going on right now may continue to lead to breakthrough treatments for people with LGSOC.
Self-care
References
Babaier A, Mal H, Alselwi W, Ghatage P. Low-grade serous carcinoma of the ovary: The current status. Diagnostics (Basel). 2022;12(2):458.
Gershenson DM. Low-grade serous carcinoma of the ovary or peritoneum. Ann Oncol. 2016;27(Suppl 1):i45-i49.
Slomovitz B, Gourley C, Carey MS, et al. Low-grade serous ovarian cancer: state of the science. Gynecol Oncol. 2020;156(3):715-725.
Harvard Health. Certain symptoms may be early signs of ovarian cancer. Accessed April 14, 2025. https://www.health.harvard.edu/cancer/certain-symptoms-may-be-early-signs-of-ovarian-cancer
Grisham RN, Slomovitz BM, Andrews N, et al. Low-grade serous ovarian cancer: expert consensus report on the state of the science. Int J Gynecol Cancer. 2023;33(9):1331-1344.
Norton TR, Manne SL, Rubin S, et al. Prevalence and predictors of psychological distress among women with ovarian cancer. J Clin Oncol. 2004;22(5)919-926.
MD Anderson Cancer Center. Social & emotional impacts of cancer. Accessed April 14, 2025. https://www.mdanderson.org/patients-family/life-after-cancer/social-emotional-impacts.html
Everyday Health. Is it ovarian cancer or is it IBS? Accessed April 9, 2025. https://www.everydayhealth.com/ovarian-cancer/is-it-ovarian-cancer-or-ibs.aspx
Healthline. Understanding low-grade ovarian cancer and its effects. Accessed June 18, 2025. https://www.healthline.com/health/ovarian-cancer/low-grade-ovarian-cancer
